We need the right data • diagnostics • vaccines before outbreaks become epidemics.







Work view

Poster: Secure Interrogation of Genomic Databases — ASM Biothreats 2018

We developed the Secure Interrogation of Genomic Databases (SIG-DB) algorithm to enable the interrogation of a privately held database with a sequence of interest to determine the presence of similar sequences, without compromising the query or database information.

Read More

GEMstone 2.0: Secure Interrogation of Genomic Databases — Project Report

IQT Labs has explored the application of secure computational information sharing techniques to enable a “query in place” approach while still maintaining the privacy of both query and database entities.

Read More

GEMstone 2.0: Detecting Evidence of Genetic Engineering — Project Report

IQT Labs B.Next and Lab41 have explored how applying machine learning (ML) approaches to DNA sequence analysis may provide “triage” tools that enable users to quickly assess the likelihood that the genome of a suspect organism has been engineered.

Read More

The Promise of Ubiquitous DNA Sequencing: Sequencers as Sensors

This paper explores how new DNA sequencing technology is poised to transform epidemic detection and management through the broad availability of inexpensive, portable, and increasingly powerful devices.

Read More

Interactive Data Visualization for Public Health Applications: An Evaluation of Plotly’s Capabilities

This report outlines the methods and results of a B.Next project with Plotly, a company that creates open source tools for visualization, to further develop their existing web-based interface to create interactive cross-filtering visualizations with multivariate datasets for non-coders.

Read More

Tackling the Next Epidemic: Data Technology to the Rescue

Integrating novel and available data technologies into public health practice will improve situational awareness, help shape outbreak interventions more precisely, facilitate faster and more efficient response activities, and save lives.

Read More

Tech Corner – A Technology Overview from IQT Portfolio Company Quanterix

To supplement the IQT Quarterly’s focus on technology trends, Tech Corner provides a practitioner’s point of view of a current challenge in the field and insight into an effective response.

Read More

The Weakest Link in Diagnostics May Be the Sample Itself

In the past two decades, two trends have given rise to a revolution in the next generation of diagnostic technologies.

Read More

Five Major Challenges for Pandemic Prediction and Prevention

Pandemics (diseases that spread globally) are rare events that are often devastating, causing substantial mortality and economic damage. Just like hurricanes or earthquakes, efforts to understand the origins of pandemics and predict their emergence would help reduce their impact and ultimately prevent them.

Read More

IQT Lab B.Next and the National Security Implications of 21st Century Life Sciences

B.Next, an IQT Lab, will explore a complex and increasingly urgent problem: how can we rapidly detect and quench epidemics of infectious disease.

Read More

In Silico Vaccine Design: Accelerating the Response to BioThreats and Emerging Infectious Disease

Smallpox, polio, measles — control of these lethal diseases is possible because of vaccines.

Read More

Early Warning for Infectious Disease Outbreaks: A Q&A with Larry Madoff

An interview with Larry Madoff, Editor of The Program for Monitoring Emerging Diseases (ProMED-mail).

Read More

Capabilities and Problems Associated with Detecting Engineered Microorganisms & Deducing Function

This paper reports on a September 15, 2016 Roundtable Discussion convened by B.Next, an IQT Lab.

Read More

Portable Sequencing for Infectious Disease Detection, Diagnosis, Discrimination, & Discovery

This paper reports on a February 28, 2017 Roundtable Discussion convened by B.Next, an IQT Lab.

Read More

The Biorevolution is Enabling New Opportunities

We are living through a period of what may justly be called a revolution in our understanding of living organisms and how they operate.

Read More

Biothreats Need to be Recognized as a Top National Security Concern

Large-scale, lethal epidemics are becoming more frequent, affecting more people, and spreading faster and farther than has been the case historically.

Read More

Outbreaks, Attacks and Accidents: Combatting Biological Threats

Testimony to the U.S. House of Representatives Committee on Energy and Commerce Subcommittee on Oversight and Investigation.

Read More

Building an effective defense against biological threats: the Technology Advantage

The United States faces significant and growing national security threats from increasingly frequent and disruptive natural epidemics of infectious disease.

Read More

On our Radar: Defeating Infectious Disease

Why do outbreaks of infectious disease occur? Can we predict them? How do they spread? How can we respond to outbreaks more effectively? What is the role of technology in this response?

Read More